Skip to main content

Table 1 The inhibition of β-catenin expression by ShRNA or MSeA is associated with drug-induced growth inhibition of tumor cells

From: Targeting the oncogenic protein beta-catenin to enhance chemotherapy outcome against solid human cancers

HCT-8 cell line % cell growth inhibition Beta-catenin expression
Control 0% ++++/strong
MSeA (1 μM) ~50% ++/weak
SN-38(0.7 μM) ~20% ++++/strong
MSeA+SN-38 >95% +/very weak
ShRNA 0% ++/weak
ShRNA+SN38 ~70% +/very weak