Skip to main content

Table 1 Tumorigenicity of PC3-derived clones, assayed in scid mice.

From: PC3 prostate tumor-initiating cells with molecular profile FAM65Bhigh/MFI2low/LEF1low increase tumor angiogenesis

Cell clone

Tumorigenicity at different cell doses

 

8 × 105

1 × 105

1 × 104

No. of tumors/No. of inoculations

   

Parent PC3

4/4

4/4

3/4

Holoclone 2G7

4/4

4/4

3/4

Paraclone 2B6

3/4

1/4

0/4

  1. Tumor formation was scored on day 30 after tumor cell inoculation for tumors seeded at 8 × 105 cells per site, and on day 46 for tumors seeded at 105 and 104 cells; the absence of a tumor was confirmed by dissection. Three other paraclones were tested and showed a tumor incidence of 1/4 (clone 4C1) or 0/4 (clones 4E10 and 5C6).
Back to article page

Molecular Cancer

ISSN: 1476-4598