|
Cell clone
|
Tumorigenicity at different cell doses
|
|---|
| |
8 × 105
|
1 × 105
|
1 × 104
|
|---|
|
No. of tumors/No. of inoculations
| | | |
|
Parent PC3
|
4/4
|
4/4
|
3/4
|
|
Holoclone 2G7
|
4/4
|
4/4
|
3/4
|
|
Paraclone 2B6
|
3/4
|
1/4
|
0/4
|
- Tumor formation was scored on day 30 after tumor cell inoculation for tumors seeded at 8 × 105 cells per site, and on day 46 for tumors seeded at 105 and 104 cells; the absence of a tumor was confirmed by dissection. Three other paraclones were tested and showed a tumor incidence of 1/4 (clone 4C1) or 0/4 (clones 4E10 and 5C6).
