Skip to main content

Advertisement

Table 1 Tumorigenicity of PC3-derived clones, assayed in scid mice.

From: PC3 prostate tumor-initiating cells with molecular profile FAM65Bhigh/MFI2low/LEF1low increase tumor angiogenesis

Cell clone Tumorigenicity at different cell doses
  8 × 105 1 × 105 1 × 104
No. of tumors/No. of inoculations    
Parent PC3 4/4 4/4 3/4
Holoclone 2G7 4/4 4/4 3/4
Paraclone 2B6 3/4 1/4 0/4
  1. Tumor formation was scored on day 30 after tumor cell inoculation for tumors seeded at 8 × 105 cells per site, and on day 46 for tumors seeded at 105 and 104 cells; the absence of a tumor was confirmed by dissection. Three other paraclones were tested and showed a tumor incidence of 1/4 (clone 4C1) or 0/4 (clones 4E10 and 5C6).