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Table 4 The association of the number of CD8+ Foxp3+ TIL, Foxp3+ Granzyme B+ TIL and the ratio of CD8+ Foxp3+ to CD8+ and GranzymeB+ Foxp3+ to Foxp3 TIL and clinicopathological characteristics in NPC patients

From: Different subsets of tumor infiltrating lymphocytes correlate with NPC progression in different ways

Characteristics CD8+Foxp3+ Granzyme B+Foxp3+
  ≤0.90 (n = 53) > 0.90 (n = 53) P ≤1.80 (n = 54) > 1.80 (n = 52) P
Age, years       
≤49 24 31   26 29  
> 49 29 22 0.174 28 23 0.432
Gender       
Male 39 45   42 42  
Female 14 8 0.151 12 10 0.704
Tumor (T) stage       
T1+T2 25 32   29 28  
T3+T4 28 21 0.173 25 24 0.988
Lymphoid Nodal (N) status       
N0 14 4   10 8  
N1-3 39 49 0.010* 44 44 0.866
TNM Clinical stage       
I + II 18 20   19 19  
III+IVa+IVb 35 33 0.685 35 33 0.885
LMP1       
- 23 33   30 26  
+ 27 20 0.098 22 25 0.494
  1. Note. *P < 0.05, as determined by the Pearson chi2 test.