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Table 4 The association of the number of CD8+ Foxp3+ TIL, Foxp3+ Granzyme B+ TIL and the ratio of CD8+ Foxp3+ to CD8+ and GranzymeB+ Foxp3+ to Foxp3 TIL and clinicopathological characteristics in NPC patients

From: Different subsets of tumor infiltrating lymphocytes correlate with NPC progression in different ways

Characteristics

CD8+Foxp3+

Granzyme B+Foxp3+

 

≤0.90

(n = 53)

> 0.90

(n = 53)

P

≤1.80

(n = 54)

> 1.80

(n = 52)

P

Age, years

      

≤49

24

31

 

26

29

 

> 49

29

22

0.174

28

23

0.432

Gender

      

Male

39

45

 

42

42

 

Female

14

8

0.151

12

10

0.704

Tumor (T) stage

      

T1+T2

25

32

 

29

28

 

T3+T4

28

21

0.173

25

24

0.988

Lymphoid Nodal (N) status

      

N0

14

4

 

10

8

 

N1-3

39

49

0.010*

44

44

0.866

TNM Clinical stage

      

I + II

18

20

 

19

19

 

III+IVa+IVb

35

33

0.685

35

33

0.885

LMP1

      

-

23

33

 

30

26

 

+

27

20

0.098

22

25

0.494

  1. Note. *P < 0.05, as determined by the Pearson chi2 test.