Table 1 The expression of Mel-18, BMI1, pAkt, and p16; and the correlations between these proteins in gastric cancer tissues and normal gastric mucosa tissues.
From: BMI1 and Mel-18 oppositely regulate carcinogenesis and progression of gastric cancer
| Â | Mel-18 n (%) | Â | BMI1 n (%) | Â | pAkt n (%) | Â | p16 n (%) | Â | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Â | (-) | (+) | P value | (-) | (+) | P value | (-) | (+) | P value | (-) | (+) | P value | |
Tissues | |||||||||||||
   Normal mucosa | 9(42.9) | 12(57.1) |  | 20(95.2) | 1(4.8) |  | 18(85.7) | 3(14.3) |  | 6(28.6) | 15(71.4) |  | |
   Gastric cancer | 59(78.7) | 16(21.3) | 0.001* | 32(42.7) | 43(57.3) | <.0001* | 33(44.0) | 42(56.0) | 0.0007* | 32(42.7) | 43(57.3) | 0.243 | |
Proteins | |||||||||||||
   Bmi-1 | |||||||||||||
Negative (-) | 29(56.9) | 22(43.1) | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | |
Positive (+) | 38(86.4) | 6(13.7) | 0.002* | Â | Â | Â | Â | Â | Â | Â | Â | Â | |
   pAkt | |||||||||||||
Negative (-) | 36(72.0) | 14(28.0) | Â | 35(70.0) | 15(30.0) | Â | Â | Â | Â | Â | Â | Â | |
Positive (+) | 32(69.6) | 14(30.4) | 0.793 | 17(37.0) | 29(63.0) | 0.0012* | Â | Â | Â | Â | Â | Â | |
   p16 | |||||||||||||
Negative (-) | 31(81.6) | 7(18.4) | Â | 11(28.9) | 27(71.1) | Â | 18(47.4) | 20(52.6) | Â | Â | Â | Â | |
Positive (+) | 37(63.8) | 21(36.2) | 0.061 | 41(70.7) | 17(29.3) | <.0001* | 33(56.9) | 25(43.1) | 0.360 | Â | Â | Â | |