Table 1 Summary of the promoter hypermethylation frequencies and expression analysis of candidate genes in ALL.

ARHGAP20

6/10

4/12 (33)

33/51 (65)

0/8

YES

ATG16L2

3/7

5/12 (42)

14/52 (27)

0/8

ND

BARHL2†

5/6

3/12 (25)

39/51 (77)

0/9

YES

BMP2†

6/7

7/12 (58)

2/52 (4)

0/8

YES

CDC14B

5/7

4/12 (33)

21/48 (44)

0/9

YES

CYP1B1†

5/6

5/12 (42)

40/52 (77)

0/10

YES

DUSP4

1/6

3/12 (25)

13/52 (25)

0/6

ND

EBF2

5/6

10/12 (83)

49/52 (94)

1/10

YES

EYA2

5/7

3/12 (25)

15/47 (32)

0/10

YES

FAT1†

1/6

3/12 (25)

34/52 (65)

0/10

YES

FOXF2

4/6

3/12 (25)

15/52 (29)

0/9

YES

GPR123

5/7

4/12 (33)

10/48 (21)

0/9

YES

HLA-F

4/6

4/12 (33)

7/52 (14)

1/10

ND

KNDC1

4/7

1/12 (8)

9/40 (23)

0/9

YES

MYO10†

6/8

6/12 (50)

8/51 (16)

1/8

YES

NKX2-1

5/6

5/12 (42)

32/51 (63)

0/9

YES

N2RE1

6/6

4/12 (33)

19/49 (39)

0/8

YES

NR4A2†

3/7

6/12 (50)

5/51 (10)

0/9

ND

PAX2

6/7

2/10 (20)

15/34 (44)

0/9

YES

PAX6

3/6

6/12 (50)

35/52 (67)

0/10

YES

POU4F1

1/6

5/12 (42)

22/51 (43)

0/8

YES

PRDM12

6/6

6/12 (50)

30/45 (67)

0/9

YES

PTGS2†

4/6

6/12 (50)

48/52 (92)

0/10

YES

SALL3

5/6

4/12 (33)

25/52 (48)

0/9

YES

SSPN

7/9

4/12 (33)

32/52 (62)

0/8

YES

TCF2†

5/6

6/12 (50)

5/52 (10)

0/10

YES

TFAP2A

5/6

5/11 (46)

33/49 (67)

0/10

YES

TFAP2C

2/6

10/12 (83)

43/50 (86)

0/10

YES

TP53I11

3/6

3/12 (25)

8/52 (15)

0/9

ND

TRPC4

5/5

9/12 (75)

48/52 (92)

0/10

YES

TSHZ3†

4/6

0/12 (0)

16/52 (31)

0/10

ND

UBE2C

3/6

2/12 (17)

12/52 (23)

0/10

YES