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Table 3 Summary of the promoter hypermethylation frequencies in epithelial cancer cell lines.

From: A Genome-wide screen identifies frequently methylated genes in haematological and epithelial cancers

Gene Colorectal LUNG BREAST KIDNEY GLIOMA Prostate
ATG16L2 0/9 2/13 1/9 7/10 1/6 0/5
BARHL2* 4/4 3/9 0/3 4/4 ND 3/5
BMP2 4/9 2/14 3/9 0/11 2/7 1/5
CDC14B 0/9 0/14 0/8 0/11 0/7 0/5
CYP1B1 7/9 2/14 1/9 3/5 1/7 2/5
EBF2* 7/9 9/13 4/9 7/10 0/7 0/4
EYA2 2/5 1/11 1/9 1/8 2/6 1/5
FAT1 0/9 1/14 0/9 0/11 0/6 0/5
FOXF2 6/10 0/14 2/9 7/12 3/7 1/5
GPR123* 5/6 5/13 5/9 6/12 1/7 2/5
HLA-F 5/9 8/14 0/9 3/12 1/7 1/5
KNDC1 0/9 0/11 0/9 0/11 1/7 1/5
NKX2-1 3/8 0/12 0/1 2/4 0/1 1/4
NR2E1* 8/9 5/14 5/8 9/11 2/6 4/4
NR4A2 0/9 2/13 0/9 2/12 0/7 4/5
PAX2 3/5 3/10 1/6 1/9 0/5 0/5
PAX6* 6/8 11/12 8/9 7/11 3/7 ND
POU4F1* 6/7 6/13 4/8 7/9 5/7 3/5
PRDM12 3/4 0/4 0/0 6/6 0/0 ND
PTGS2 3/9 1/14 1/9 1/12 1/7 2/5
SALL3* 8/8 6/12 6/8 8/8 5/7 3/5
TCF2* 5/9 8/12 5/9 0/12 5/7 2/5
TFAP2A* 5/9 9/14 2/9 5/7 7/8 1/5
TFAP2C 0/8 3/13 0/9 2/11 1/6 0/5
TP53I11* 2/9 3/13 5/9 8/12 4/7 2/5
TRPC4 8/9 5/14 5/9 4/11 1/7 1/5
TSHZ3 6/7 4/13 3/7 2/11 0/7 ND
UBE2C 0/9 0/14 0/9 0/8 0/6 0/4
  1. The table summarises all of the genes assessed for hypermethylation across cell lines from six epithelial cancers. The symbol * indicates genes showing methylation frequency of 50% or above in 3 or more epithelial cancer cell lines.