Skip to main content

Table 3 Summary of the promoter hypermethylation frequencies in epithelial cancer cell lines.

From: A Genome-wide screen identifies frequently methylated genes in haematological and epithelial cancers

Gene

Colorectal

LUNG

BREAST

KIDNEY

GLIOMA

Prostate

ATG16L2

0/9

2/13

1/9

7/10

1/6

0/5

BARHL2*

4/4

3/9

0/3

4/4

ND

3/5

BMP2

4/9

2/14

3/9

0/11

2/7

1/5

CDC14B

0/9

0/14

0/8

0/11

0/7

0/5

CYP1B1

7/9

2/14

1/9

3/5

1/7

2/5

EBF2*

7/9

9/13

4/9

7/10

0/7

0/4

EYA2

2/5

1/11

1/9

1/8

2/6

1/5

FAT1

0/9

1/14

0/9

0/11

0/6

0/5

FOXF2

6/10

0/14

2/9

7/12

3/7

1/5

GPR123*

5/6

5/13

5/9

6/12

1/7

2/5

HLA-F

5/9

8/14

0/9

3/12

1/7

1/5

KNDC1

0/9

0/11

0/9

0/11

1/7

1/5

NKX2-1

3/8

0/12

0/1

2/4

0/1

1/4

NR2E1*

8/9

5/14

5/8

9/11

2/6

4/4

NR4A2

0/9

2/13

0/9

2/12

0/7

4/5

PAX2

3/5

3/10

1/6

1/9

0/5

0/5

PAX6*

6/8

11/12

8/9

7/11

3/7

ND

POU4F1*

6/7

6/13

4/8

7/9

5/7

3/5

PRDM12

3/4

0/4

0/0

6/6

0/0

ND

PTGS2

3/9

1/14

1/9

1/12

1/7

2/5

SALL3*

8/8

6/12

6/8

8/8

5/7

3/5

TCF2*

5/9

8/12

5/9

0/12

5/7

2/5

TFAP2A*

5/9

9/14

2/9

5/7

7/8

1/5

TFAP2C

0/8

3/13

0/9

2/11

1/6

0/5

TP53I11*

2/9

3/13

5/9

8/12

4/7

2/5

TRPC4

8/9

5/14

5/9

4/11

1/7

1/5

TSHZ3

6/7

4/13

3/7

2/11

0/7

ND

UBE2C

0/9

0/14

0/9

0/8

0/6

0/4

  1. The table summarises all of the genes assessed for hypermethylation across cell lines from six epithelial cancers. The symbol * indicates genes showing methylation frequency of 50% or above in 3 or more epithelial cancer cell lines.