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Figure 7 | Molecular Cancer

Figure 7

From: Pregnane × Receptor (PXR) expression in colorectal cancer cells restricts irinotecan chemosensitivity through enhanced SN-38 glucuronidation

Figure 7

A, UGT1As mRNA expression levels in pcDNA3, PXR2, PXR3 and PXR6 cells. Results were obtained from six separate experiments; bars, SEM. ** p < 0.01, * p < 0.05 (student's t-test) compared to CTRL cells. B, UGT1A1 mRNA expression levels in CTRL-Mock, PXR2-Mock, PXR2-sh1334 and PXR2-sh2116 cells. Results were obtained from four separate experiments; bars, SEM. *** p < 0.001, * p < 0.05 (student's t-test) compared to CTRL-Mock cells.

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