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Table 3 Ratio of the forward (BRCA2) and the reverse (ZAR2) activity in the G0/G1 and S/G2 growth phases of different breast cancer cells using transient transfection with the dual reporter/promoter construct (see Fig. 1B).

From: Cell cycle-dependent regulation of the bi-directional overlapping promoter of human BRCA2/ZAR2 genes in breast cancer cells

Growth Phase

Ratio of Rluc/Fluc activities* in

 

MCF7

MDA-MB-468

MDA-MB-231

BT549

G0/G1

0.125 ± 0.03

0.23 ± 0.06

0.33 ± 0.01

0.28 ± 0.07

S/G2

3.25 ± 0.14

3.12 ± 0.11

2.5 ± 0.12

3.31 ± 0.13

  1. *Results are mean ± SE (n = 6)