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Table 2 Methylation frequencies in lung, colorectal and prostate cancers.

From: Identification of 5 novel genes methylated in breast and other epithelial cancers

  CIDE-A DBC1 EMILIN2 FBLN2 SALL1
Lung tumour lines 11/15 not done 4/10 7/9 4/13
Lung tumours 1/16 not done 1/13 0/11 4/16
Lung benign 0/16 not done 1/17 0/10 3/17
Colorectal tumour lines 8/8 8/8 4/5 4/4 6/6
Colorectal tumours 7/8 8/8 19/57 54/58 44/53
Colorectal adenomas 7/7 8/8 7/22 23/23 17/19
Colorectal benign 16/16 16/16 1/82 74/80 30/79
Prostate tumour lines 3/4 2/5 3/5 1/5 3/4
Prostate tumours 3/14 1/14* 0/14 5/14 5/14
Prostate benign 1/4 2/4* 0/4 0/4 1/4
  1. Methylation frequencies are shown for lung, colorectal and prostate cancer cell lines and primary tumours and normal tissue. (*) very weak methylation. DBC1 methylation in lung cancer has been demonstrated previously, hence in this study DBC1 was not analysed in lung cancer.