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Figure 4 | Molecular Cancer

Figure 4

From: CD40 ligand induced cytotoxicity in carcinoma cells is enhanced by inhibition of metalloproteinase cleavage and delivery via a conditionally-replicating adenovirus

Figure 4

Membrane-bound expression of CD40L induces apoptosis in CD40-positive carcinomas. EJ, AGS and HeLa cells were infected with 100 MOI RAdMock, RAdCD40L or RAdncCD40L, or treated with soluble CD40L (1 μg/ml) or left without treatment for 48 hours. Apoptotic cells were assessed by staining with Annexin V-APC and analysis by flow cytometry. Results are a mean of triplet samples ± SD. Two-tailed t-test RAdL vs. RAdncL: EJ, p = 0.0014; AJS, p = 0.0022; HeLa, p = 0.6560.

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Molecular Cancer

ISSN: 1476-4598