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Table 2 Summary of LIMD1 mutations

From: LIMD1 is more frequently altered than RB1 in head and neck squamous cell carcinoma: clinical and prognostic implications

   Mutations
   Exon1 Exon5
  Nucleotide change 470C → T 660A del 882C → T 967T del 1003C → A 1068T → C C del at intron4/exon5
TNM stage Amino acid change Ser157 Phe Frame shift Thr294Thr Frame shift Pro335Thr Gly356Gly Splice-juction
  Samples showing mutations        
Moderate L66 - - - - - - -
Moderate L139 - - SNPa - - + -
Severe L144 - - SNPa - - - -
Severe L126 - - SNPa - - + -
Severe L153 - - SNPa - - - -
StageI #292 - - SNPa - - - -
StageI #2642 - - - - - + -
stageII #2772 - - + - - - -
stageII #7216 - - - + - - -
stageII #2073 + - SNPa - - + -
stageII #5303 - + - - - - -
stageII #1234 - - SNPa - - SNPb -
stageII #2323 - - + - - - -
stageII #1108 - - - - - + -
stageII #7077 + - - - - - -
StageIII #821 - - - - - + -
StageIII #1367 + - - - - - -
StageIII #1552 - - SNPa - + - -
StageIII #615 - - - + - - -
StageIII #5090B - - + - - - -
StageIII #816 - - + - - - -
StageIII #326 - + SNPa - - - -
StageIII #1068 - - SNPa - + - -
StageIII #3893 - - - + - - -
StageIII #308 - + SNPa - - - -
StageIII #6433 - + SNPa - - - -
StageIII #1332 + - SNPa - - - +
StageIII #2398 - - - + - - -
StageIII #7059 - + - - - - -
StageIV #1087 - - + - - - -
StageIV #4075 - - - - - SNPb -
StageIV #2508 - + - - - + -
StageIV #5114 - - + - - - -
StageIV #5219 - + - - - - -
StageIV #1084 + - - - - SNPb -
StageIV #5184 - + - - - - -
StageIV #944 - - - - - - +
StageIV #2785 - - SNPa - - - +
StageIV #1774 - - - - - + -
Cell lines Hep2 - - SNPa - - SNPb -
  SCC084 - - SNPa - - SNPb -
Mutation frequency in HNSCC 6% (5/85) 9% (8/85) 7% (6/85) 4% (4/85) 2% (2/85) 9% (8/85) 4% (3/85)
  1. SNPa: rs267237; SNPb:rs267236; del: deletion; L: Dysplastic lesions; #: Invasive samples; '+': Presence; '-': Absence.