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Table 6 Correlation between mRNA and protein expression of RB1 and their association with LIMD1 molecular alterations.

From: LIMD1 is more frequently altered than RB1 in head and neck squamous cell carcinoma: clinical and prognostic implications

  RB1 LIMD1
Sample No.; HPV status Genetic alterations mRNA status Protein expression Genetic/epigenetic alterations mRNA status
Dysplastic lesions      
L127; HPV- D- ND Normal D+Me+Mu- ND
L139; HPV- D- ND Normal D-Me+Mu- ND
L154; HPV- D- ND Normal D+Me+Mu- ND
L162; HPV- D- ND Normal D+Me+Mu- ND
L158; HPV16 D- ND Medium D+Me+Mu- ND
HNSCC samples      
#1004; HPV- D- Normal Normal D+Me+Mu-
#5165; HPV- D- Normal Normal D+Me+Mu-
#6817;HPV16 D+ Medium D+Me+Mu-
#2884; HPV- D- Normal Normal D-Me-Mu- Normal
#1108; HPV - D+ Medium D-Me+Mu+
#1774;HPV16 D+ Low D-Me+Mu+
#872; HPV- D- Normal Normal D-Me-Mu- Normal
#5303; HPV- D- Normal Normal D-Me+Mu+
#6907;HPV16 D- Low D-Me+Mu-
#1087; HPV- D- Normal Normal D-Me-Mu+ Normal
#944; HPV- D+ Low D+Me+Mu+
#5733;HPV16 D- Normal Normal D+Me+Mu-
#6392; HPV- D- Normal Normal D-Me+Mu-
#7077; HPV- D- Normal Normal D-Me-Mu+
#797; HPV- D- Normal Normal D+Me+Mu-
Hep2, HPV18 D- Normal Normal D-Me+Mu-
UPCI:SCC084, HPV- D- Normal Normal D-Me+Mu-
  1. L: Dysplastic lesions; # HNSCC samples; D: Deletion; Me: Methylation; Mu: Mutation; '+': Positive; '-': Negative; '↓': Down expression; ND: Not done.