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Table 1 Association of clinical features of patients and immunohistochemical expression of EGFR, β-catenin, and cyclin D1.

From: Epidermal growth factor receptor regulates β-catenin location, stability, and transcriptional activity in oral cancer

 

EGFR expression

β-catenin expression

Cyclin D1 expression

 

Low

High

Mem

C/N

Low

High

Clinicopathologic features

(n = 66)

(n = 46)

(n = 86)

(n = 26)

(n = 59)

(n = 53)

Gender

      

   Male (n = 93)

56

37

70

23

55

38

   Female (n = 19)

10

9

16

3

9

10

Size

      

   ≤4.0 cm (n = 66)

43

23

55

11*

37

29

   > 4.0 cm (n = 46)

23

23

31

15

27

19

LN involvement

      

   No (n = 64)

33

31

17

23

38

26

   Yes (n = 48)

22

26

18

14

21

27

Differentiation

      

   Well (n = 41)

28

13

32

9

23

18

   Moderate (n = 43)

22

21

32

11

25

18

   Poor (n = 28)

16

12

22

6

16

12

Staging

      

   Early (n = 50)

35

15**

43

7***

30

20

   Advanced (n = 62)

31

31

43

19

34

28

  1. LN, lymph node; Mem, membranous; C/N, cytoplasmic/nuclear. *, p = 0.042; **, p = 0.025; ***, p = 0.031