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Table 1 Association of clinical features of patients and immunohistochemical expression of EGFR, β-catenin, and cyclin D1.

From: Epidermal growth factor receptor regulates β-catenin location, stability, and transcriptional activity in oral cancer

  EGFR expression β-catenin expression Cyclin D1 expression
  Low High Mem C/N Low High
Clinicopathologic features (n = 66) (n = 46) (n = 86) (n = 26) (n = 59) (n = 53)
Gender       
   Male (n = 93) 56 37 70 23 55 38
   Female (n = 19) 10 9 16 3 9 10
Size       
   ≤4.0 cm (n = 66) 43 23 55 11* 37 29
   > 4.0 cm (n = 46) 23 23 31 15 27 19
LN involvement       
   No (n = 64) 33 31 17 23 38 26
   Yes (n = 48) 22 26 18 14 21 27
Differentiation       
   Well (n = 41) 28 13 32 9 23 18
   Moderate (n = 43) 22 21 32 11 25 18
   Poor (n = 28) 16 12 22 6 16 12
Staging       
   Early (n = 50) 35 15** 43 7*** 30 20
   Advanced (n = 62) 31 31 43 19 34 28
  1. LN, lymph node; Mem, membranous; C/N, cytoplasmic/nuclear. *, p = 0.042; **, p = 0.025; ***, p = 0.031