From: Ex-vivo HRMAS of adult brain tumours: metabolite quantification and assignment of tumour biomarkers
 | Ast II | Grade III | GBM | Metastases | Meningioma | Lymphoma |
---|---|---|---|---|---|---|
Ace Ace | 0.17 ± 0.10 | 0.22 ± 0.06 | 0.19 ± 0.04 | 0.15 ± 0.02 | 0.18 ± 0.03 | 0.40 ± 0.03 |
Ala | 0.30 ± 0.13 | 1.06 ± 0.31 | 1.32 ± 0.17 | 0.81 ± 0.17 | 2.75 ± 0.46 | 2.59 ± 1.06 |
Asc | 0.46 ± 0.08 | 0.58 ± 0.09 | 0.63 ± 0.10 | 0.60 ± 0.28 | 0.82 ± 0.14 | 2.94 ± 1.41 |
Asp | 0.41 ± 0.13 | 0.37 ± 0.43 | 1.14 ± 0.33 | 0.18 ± 0.12 | 0.19 ± 0.06 | 0.73 ± 0.37 |
Bet | 0.14 ± 0.03 | 0.17 ± 0.06 | 0.25 ± 0.04 | 0.10 ± 0.02 | 0.16 ± 0.03 | 0.21 ± 0.08 |
Cho | 0.24 ± 0.05 | 0.26 ± 0.07 | 0.33 ± 0.05 | 0.23 ± 0.04 | 0.23 ± 0.04 | 0.34 ± 0.03 |
Cr | 3.31 ± 0.80 | 3.07 ± 1.35 | 2.99 ± 0.39 | 1.24 ± 0.21 | 0.65 ± 0.13 | 2.07 ± 1.39 |
Glc | 0.53 ± 0.22 | 0.19 ± 0.13 | 0.38 ± 0.12 | 0.64 ± 0.31 | 0.12 ± 0.07 | 0.55 ± 0.55 |
Glu | 1.51 ± 0.60 | 3.01 ± 1.39 | 2.60 ± 0.33 | 2.28 ± 0.46 | 4.94 ± 0.56 | 4.46 ± 0.42 |
Gln | 5.12 ± 0.56 | 4.63 ± 1.35 | 7.11 ± 0.89 | 2.13 ± 0.32 | 7.54 ± 0.92 | 5.44 ± 1.18 |
GSH | 0.52 ± 0.15 | 0.55 ± 0.11 | 0.93 ± 0.11 | 0.96 ± 0.30 | 2.04 ± 0.25 | 1.18 ± 0.07 |
GPC | 1.21 ± 0.14 | 0.77 ± 0.21 | 0.76 ± 0.14 | 0.73 ± 0.32 | 0.26 ± 0.07 | 0.42 ± 0.15 |
GPE | 0.62 ± 0.13 | 1.20 ± 0.58 | 0.41 ± 0.10 | 0.69 ± 0.15 | 1.03 ± 0.27 | 0.60 ± 0.09 |
Gly | 1.59 ± 0.54 | 1.52 ± 0.47 | 2.34 ± 0.39 | 0.75 ± 0.11 | 1.51 ± 0.22 | 2.18 ± 0.49 |
His | 0.58 ± 0.13 | 0.65 ± 0.47 | 1.67 ± 0.53 | 0.08 ± 0.06 | 0.09 ± 0.04 | 0.82 ± 0.82 |
h-Tau | 0.35 ± 0.12 | 0.58 ± 0.21 | 1.16 ± 0.23 | 0.06 ± 0.03 | 0.69 ± 0.20 | 0.36 ± 0.04 |
Ile | 0.13 ± 0.02 | 0.15 ± 0.04 | 0.11 ± 0.02 | 0.25 ± 0.06 | 0.26 ± 0.06 | 0.46 ± 0.24 |
Lac | 5.68 ± 0.66 | 8.91 ± 1.56 | 9.04 ± 1.07 | 5.40 ± 0.71 | 9.81 ± 0.89 | 8.83 ± 0.76 |
Leu | 0.26 ± 0.03 | 0.92 ± 0.46 | 0.51 ± 0.09 | 0.56 ± 0.10 | 0.62 ± 0.11 | 1.14 ± 0.45 |
Lys | 0.52 ± 0.20 | 0.61 ± 0.12 | 1.07 ± 0.12 | 1.05 ± 0.22 | 1.29 ± 0.17 | 2.31 ± 0.85 |
m-Ins | 5.23 ± 0.92 | 2.02 ± 0.83 | 2.03 ± 0.32 | 0.70 ± 0.23 | 0.30 ± 0.08 | 1.36 ± 0.40 |
NAA | 1.00 ± 0.65 | 1.14 ± 0.76 | 0.48 ± 0.15 | 0.29 ± 0.11 | 0.07 ± 0.02 | 1.08 ± 1.07 |
PCh | 0.36 ± 0.12 | 0.45 ± 0.07 | 1.56 ± 0.27 | 0.68 ± 0.11 | 0.97 ± 0.12 | 1.10 ± 0.20 |
PE | 0.18 ± 0.05 | 1.14 ± 0.76 | 1.97 ± 0.30 | 1.93 ± 0.30 | 1.87 ± 0.27 | 4.55 ± 1.72 |
s-Ins | 0.25 ± 0.05 | 0.20 ± 0.10 | 0.20 ± 0.03 | 0.10 ± 0.03 | 0.04 ± 0.01 | 0.26 ± 0.04 |
Suc | 0.11 ± 0.02 | 0.13 ± 0.04 | 0.19 ± 0.03 | 0.14 ± 0.03 | 0.28 ± 0.04 | 0.18 ± 0.02 |
Tau | 1.00 ± 0.14 | 1.00 ± 0.23 | 0.85 ± 0.11 | 1.81 ± 0.77 | 1.75 ± 0.25 | 2.25 ± 0.74 |
Thr | 0.31 ± 0.06 | 0.43 ± 0.16 | 0.66 ± 0.29 | 0.29 ± 0.07 | 0.44 ± 0.13 | 0.90 ± 0.18 |
Val | 0.20 ± 0.04 | 0.31 ± 0.11 | 0.20 ± 0.04 | 0.37 ± 0.04 | 0.38 ± 0.05 | 1.02 ± 0.45 |