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Table 6 Significant differences in metabolite concentration in binary comparisons between tumour type

From: Ex-vivo HRMAS of adult brain tumours: metabolite quantification and assignment of tumour biomarkers

Tumour type 1

Tumour type 2

Significantly higher concentration in tumour type 1

Significantly higher concentration in tumour type 2

lymphoma

Astrocytoma II

  

lymphoma

Astrocytoma III

  

lymphoma

GBM

Tau*

 

lymphoma

Metastasis

h-Tau

 

lymphoma

Meningioma

Cr*

Ala**, Glu*, Gln**, Lac*

Astrocytoma II

Astrocytoma III

  

Astrocytoma II

GBM

m-Ins*

Ala

Astrocytoma II

Metastasis

Gln*, m-Ins*,

PE*

Astrocytoma II

Meningioma

Cr**, GPC**, His**, m-Ins**, s-Ins**

Ala**, Glu*, GSH**, PE

Astrocytoma III

GBM

  

Astrocytoma III

Metastasis

h-Tau*

 

Astrocytoma III

Meningioma

GPC*, m-Ins*

GSH*, Lys

GBM

Metastasis

Cr, Gln*, Gly*, h-Tau*

 

GBM

Meningioma

Asp, Cr**, GPC*, His*, m-Ins**, NAA*, s-Ins**

Ala, Glu*, GSH**, Ile*, Tau, Val*

Metastasis

Meningioma

Cr*

Ala**, Glu*, Gln**, Lac*

  1. A non-parametric Mann-Whitney-U test was used to compare for significant differences in metabolite concentrations between two general tumour types. This was repeated for all binary comparisons of the tumour groups with a significance level of p < 0.01. Significantly higher tumours are listed by abbreviation. Higher significance levels are indicated with asterisks * = p ≤ 0.005, ** = p ≤ 0.001.