Skip to main content
Figure 1 | Molecular Cancer

Figure 1

From: DNA methylation profiling in doxorubicin treated primary locally advanced breast tumours identifies novel genes associated with survival and treatment response

Figure 1

Summary of the methylation data. A) Summary of the average DNA methylation values in percentage for the analysis of the fourteen genes (x-axis) in the 75 breast cancer samples, six normal breast tissues (on top) and the six breast cancer cell lines (bottom lines). Absence of methylation over an amplification product is shown in yellow, complete methylation in dark blue; intermediate methylation degrees by the corresponding mixtures of the two colours. B) Nonparametric correlation of methylation levels between genes and between regions within the same gene. The first row and the last column contain the gene name or gene name followed by a number that indicate different genomic regions within the same gene (Additional File 5). Green squares have been assigned to correlations that are non significant. Red square correlations are significant after FDR correction (threshold 10%). For each significant correlation 3 values are given from top to bottom: the correlation coefficient (R2 value), the p-value and the number of tested samples.

Back to article page

Molecular Cancer

ISSN: 1476-4598