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Table 1 Correlations between ATX expression and clinicopathologic variables of 38 patients with HCC.

From: Autotaxin expression and its connection with the TNF-alpha-NF-κB axis in human hepatocellular carcinoma

Clinicopathologic variables

 

ATX expression

P

 

Subtotal

0

1+

2+

3+

 

Age

     

P = 1

< = 50

6

1

1

1

3

 

>50

29

3

4

6

16

 

Gender

     

P = 0.836

Male

32

3

7

5

17

 

Female

6

1

1

0

4

 

Etiology

     

P = 0.0053

HBV

7

0

0

0

7

 

HCV

11

0

2

1

8

 

NASH

10

0

3

2

5

 

Normal-HCC

10

4

3

2

1

 

Inflammation

     

P = 0.00031

Without

10

4

3

2

1

 

With

28

0

5

3

20

 

Tumor grade

     

P = 0.932

   I

22

2

4

3

13

 

   II

9

2

3

1

6

 

   III

4

0

1

1

2

 

Lymphovascular invasion

     

P = 0.414

Absence

26

2

5

4

15

 

Presence

9

2

3

1

3

 

Tumor nodule no.

     

P = 0.927

   Multiple(> = 2)

8

1

1

1

5

 

   Solitary

27

3

7

4

13

 

Serum AFP (ug/L)

     

P = 0.3585

   < = 20

22

1

6

3

12

 

   >20

7

1

0

1

5

 

Liver cirrhosis

     

P = 0.0003

Absence

10

4

3

2

1

 

Presence

28

0

5

3

20

 
  1. Note: The expression of ATX was determined in 38 cases of HCC by immunohistochemical studies as described in Materials and Methods. The correlations between ATX expression and clinicopathologic variables of HCCs were evaluated by the Fisher exact test. Statistically significant values are in bold. Some clinicopathologic factors only included 35 or less cases information as several cases missed part of the clinicopathologic information.
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Molecular Cancer

ISSN: 1476-4598