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Table 1 Correlations between ATX expression and clinicopathologic variables of 38 patients with HCC.

From: Autotaxin expression and its connection with the TNF-alpha-NF-κB axis in human hepatocellular carcinoma

Clinicopathologic variables   ATX expression P
  Subtotal 0 1+ 2+ 3+  
Age       P = 1
< = 50 6 1 1 1 3  
>50 29 3 4 6 16  
Gender       P = 0.836
Male 32 3 7 5 17  
Female 6 1 1 0 4  
Etiology       P = 0.0053
HBV 7 0 0 0 7  
HCV 11 0 2 1 8  
NASH 10 0 3 2 5  
Normal-HCC 10 4 3 2 1  
Inflammation       P = 0.00031
Without 10 4 3 2 1  
With 28 0 5 3 20  
Tumor grade       P = 0.932
   I 22 2 4 3 13  
   II 9 2 3 1 6  
   III 4 0 1 1 2  
Lymphovascular invasion       P = 0.414
Absence 26 2 5 4 15  
Presence 9 2 3 1 3  
Tumor nodule no.       P = 0.927
   Multiple(> = 2) 8 1 1 1 5  
   Solitary 27 3 7 4 13  
Serum AFP (ug/L)       P = 0.3585
   < = 20 22 1 6 3 12  
   >20 7 1 0 1 5  
Liver cirrhosis       P = 0.0003
Absence 10 4 3 2 1  
Presence 28 0 5 3 20  
  1. Note: The expression of ATX was determined in 38 cases of HCC by immunohistochemical studies as described in Materials and Methods. The correlations between ATX expression and clinicopathologic variables of HCCs were evaluated by the Fisher exact test. Statistically significant values are in bold. Some clinicopathologic factors only included 35 or less cases information as several cases missed part of the clinicopathologic information.