Figure 4

Negative role of PCBP1 in tumor cell invasion. (A) Invasion assays of HepG2 cell transfected with negative control siRNA (N.C) or siPCBP1-1 or siv6-1. Quantitation of tumor cell invasion was described in (B). The percentage of cell invasion was normalized to that of cells transfected with control vector. (C) HepG2 cells were transfected with the vectors just as indicated for 24 hours and cell invasion assay was performed. Quantitation of tumor cell invasion was described in (D). The data are mean ± SD of at least three independent studies, each performed in triplicate. The statistical difference between the samples was demonstrated as * p ≤ 0.05 or ** p ≤ 0.001.