Quantitative proteomics identification of phosphoglycerate mutase 1 as a novel therapeutic target in hepatocellular carcinoma

Table 4 Relevance of HCC characteristics to PGAM1 immunoreactivity: histodifferentiation to PGAM1.

Histodifferentiation Grading	Cases	+	+ +	+ + +^a	Total Score	Average Score^b
Well differentiated	11	73% (8/11)	18% (2/11)	9% (1/11)	63	5.73 ± 2.46
Moderately differentiated	28	36% (10/28)	39% (11/28)	25% (7/28)	217	7.75 ± 2.68
Poorly differentiated	15	0	7% (1/15)	93% (14/15)	148	9.87 ± 3.17

^a Cross χ² test, p < 0.01.
^bOne-way ANOVA analysis, p < 0.05; LSD-t test, p < 0.05 (well versus moderately; well versus poorly; moderately versus poorly).

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