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Figure 4 | Molecular Cancer

Figure 4

From: PI3Kp110-, Src-, FAK-dependent and DOCK2-independent migration and invasion of CXCL13-stimulated prostate cancer cells

Figure 4

Role of Src and FAK in PCa cell migration and invasion. LNCaP and PC3 cell lines were tested for their ability to invade Matrigel™ Matrix and migrate through an 8.0 μm porous membrane in the presence or absence of CXCL13, anti-human CXCR5 antibody, SU6656, and PF-573228. Cells that invaded or migrated to the lower surface of the membrane were stained with crystal violet and counted by microscopy at 40× magnification. Percent cell invasion was calculated following manufacturer's instructions (BD Biosciences). Asterisks indicate significant differences (p < 0.05) between CXCL13-treated and untreated cells.

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Molecular Cancer

ISSN: 1476-4598