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Figure 6 | Molecular Cancer

Figure 6

From: PI3Kp110-, Src-, FAK-dependent and DOCK2-independent migration and invasion of CXCL13-stimulated prostate cancer cells

Figure 6

CXCL13-CXCR5 signaling events required for ERK1/2 activation. FACE assays were performed to measure active and total ERK1/2 levels in LNCaP and PC3 cell lines. Cells were treated with (or without) CXCL13 for 5 or 10 minutes, along with or without CXCR5 blockade, pertussis toxin, U-73122, wortmannin, PI-103, TGX221, and AS605240, DOCK2 siRNA, SU6656, and PF-573228. Experiments were performed in triplicate and results show the ratio of p-ERK1/2 to total ERK1/2.

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Molecular Cancer

ISSN: 1476-4598