Figure 2
From: Doxorubicin and etoposide sensitize small cell lung carcinoma cells expressing caspase-8 to TRAIL
SCLC cell lines significantly differ in expression of proteins involved in TRAIL signaling. The level of (A) pro-caspase-8, -2, -10, (B) FADD, cFLIPL, cFLIPS, and (C) survivin, Mcl-1, and Bcl-2 proteins in H69, H82, U1285, U1690, and U1906 cells. An equal loading was controlled using anti-β-actin antibody. Jurkat cells were used as a positive control for expression of caspase-10. Results are representative of three independent experiments.