From: Doxorubicin and etoposide sensitize small cell lung carcinoma cells expressing caspase-8 to TRAIL
% of cells | Control | TRAIL | Doxorubicin | TRAIL+Doxorubicin |
---|---|---|---|---|
Decreased MMP | 2.3 ± 0.6 | 2.2 ± 0.7 | 13.4 ± 1.8 * | 29.8 ± 6.3 *+x |
Active Bax | 1.5 ± 0.9 | 2.8 ± 0.4 | 11.9 ± 3.5 * | 44.1 ± 5.3 *+x |
Sub-G1 | 4.9 ± 0.6 | 5.2 ± 0.5 | 21.9 ± 3.4 +* | 40.4 ± 1.7 *+x |