Figure 5
Monitoring of HCC progression in c-myctg mice. (A) Periodical measurement of tumor growth in an alb-myctg mouse liver at 47, 52, 58 and 63 weeks of age in T1-weighted contrast-enhanced and T2-weighted sequences. Red circle: tumor node measured for volumetric statistics. (B) Chronological progression of tumor growth within 15 weeks demonstrated on one representative tumor node. Volumetric data was obtained using an off-line workstation. (C) Measurement of increasing mouse total liver volume within 15 weeks. Median of three independent measurements is shown. Orientation labeling: R: right; L: left.