Figure 8

Co-treatment with small-molecule inhibitors of NF-κB, STAT3 and/or PI3K additively inhibits the proliferation of iMyc^Eμ-1 cells. MTS/PMS cell proliferation assay after 24-hour treatment with low doses of LY, LC and WHI in isolation or in various combinations, as indicated. Box at the bottom gives the average percent (%) growth inhibition. Data were normalized to DMSO-treatment controls, and error bars represent the standard deviation from a representative experiment performed in triplicate.