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Figure 4 | Molecular Cancer

Figure 4

From: Activation of the NF-κB pathway as a mechanism of alcohol enhanced progression and metastasis of human hepatocellular carcinoma

Figure 4

Effects of ethanol on tumor angiogenesis in a 3-D model in vitro. Tumor angiogenesis was analyzed using a 3-D co-culture system as described in Materials and methods. (A) Representative images of sprouts from HUVEC cells with bead under various culture conditions are shown. (B) HUVEC and HepG2 co-cultures were treated with ethanol (0.2%) with/without PDTC (20 μM). The angiogenesis which was indicated by the growth of endothelial sprouts was measured. (C) HUVEC and HepG2 co-cultures were treated with ethanol (0.2%) with/without C3G (20 μM). The angiogenesis which was indicated by the growth of endothelial sprouts was measured. **P < 0.01, n = 3.

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Molecular Cancer

ISSN: 1476-4598