Molecular Cancer

Table 2 Odds ratios of TNM stage and vessel invasiveness in relation to different levels of alcohol consumption

From: Activation of the NF-κB pathway as a mechanism of alcohol enhanced progression and metastasis of human hepatocellular carcinoma

	TNM I-II		TNM III-IV
	Control(n = 39)		Cases(n = 13)		Odds ratio ^*	95% confidence interval		P -Value
	NO.	%	NO.	%	Odds ratio ^*	95% confidence interval		P -Value
Average ethanol intake
0	25	64.2	3	23.1	1.00^†			x
Low(<35 g/d)	7	17.9	2	15.4	5.81	0.42	80.57	0.190
Moderate(≥35 < 87.5 g/d) & High(≥87.5 g/d)	7	17.9	8	61.5	22.99	2.13	248.91	0.010^a
Vessel invasiveness
	Control(n = 43)		Cases(n = 9)		Odds ratio ^*	95% confidence interval		P -Value
	NO.	%	NO.	%	Odds ratio ^*	95% confidence interval		P -Value
Average ethanol intake
0	27	62.8	1	11.1	1.00^†
Low(<35 g/d)	8	18.6	1	11.1	2.05	0.09	46.40	0.653
Moderate(≥35 < 87.5 g/d) & High(≥87.5 g/d)	8	18.6	7	77.8	21.04	1.61	275.56	0.020^a

^*Adjusted for sex, age, HBV infection and liver function (Child grade).
^†Reference category.
^a P < 0.05.

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ISSN: 1476-4598

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