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Figure 1 | Molecular Cancer

Figure 1

From: SPOCK1 as a potential cancer prognostic marker promotes the proliferation and metastasis of gallbladder cancer cells by activating the PI3K/AKT pathway

Figure 1

Clinical significance of SPOCK1 in human GBC. (A) Scatterplots of the relative expression of SPOCK1 in GBC tissues and their matched nontumor counterparts. SPOCK1 expression was calculated and is expressed as the SPOCK1/GADPH expression ratio (2-ΔCT). (B) Comparison of the SPOCK1 expression level between GBC tissues and their corresponding nontumor tissues. (C) Representative image of GBC staining with an anti-SPOCK1 antibody. (a, b) Weak expression of SPOCK1 in well and moderately differentiated GBC tissues; (c) strong expression of SPOCK1 in poorly differentiated GBC tissues (scale bar, 100 μm). (D) Scatterplots of the average staining scores of SPOCK1 expression in patients with or without metastasis. (E) Kaplan-Meier overall survival curve of GBC patients correlated with SPOCK1 expression.

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