Figure 3

Boxplot profile of ID2 and ID3 expression in the seven molecular sub-types of CLL identified by consensus clustering. For each molecular sub-type (clusters 1–7), the distribution of relative ID2/ID3 expression values is shown together with the log₂ fold-change (FC) and significance level of the difference between the mean expression for the sub-type compared to all other sub-types. Significant differences that indicate over- or under-expression of Id genes in individual sub-types are highlighted in bold-face. P values were corrected for false discovery rate [51].