Figure 4From: Receptor protein tyrosine phosphatase beta/zeta is a functional binding partner for vascular endothelial growth factor RPTPβ/ζ is required for VEGF 165 -induced endothelial cell migration. Effect of VEGF165 on HUVEC migration after down-regulation of RPTPβ/ζ expression by two different siRNAs. Data are from five independent experiments and are expressed as mean ± s.e.m. percentage change in number of migrating cells compared with the non stimulated untransfected cells (set as default 100). Untrasfected, untransfected HUVEC; siNeg, HUVEC transfected with a negative control siRNA; siRPTPβ/ζ1, HUVEC transfected with siRPTPβ/ζ#1; siRPTPβ/ζ2, HUVEC transfected with si RPTPβ/ζ#2. The Western blot on top shows effective down-regulation of RPTPβ/ζ by both siRNA sequences used.Back to article page