The expression of active/inactive GSK3β proteins in various cellular compartments in normal/OTSCC tissues samples. (A) The representative photomicrograph shows GSK3β expression in the (a) nuclear compartment (NC) and (b) cytoplasmic compartment (CC) of a normal tongue (200X). (c) GSK3β expression in the nuclear and cytoplasmic compartments (N-CC) in a WDSCC of OTSCC (100X). (B) pS9GSK3β expression in the (a) cytoplasmic compartment in a MDSCC of an OTSCC sample and (b) the nuclear compartment in a PDSCC of an OTSCC sample. (C) A graph showing the percentage of samples of an initial grade (grade-1) or a higher grade (grade 2–3) showing pS9GSK3β expression and the shifting of pS9GSK3β from the cytoplasm to the nucleus trend in the higher grade samples (p = 0.01).