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Figure 3 | Molecular Cancer

Figure 3

From: Expression and inactivation of glycogen synthase kinase 3 alpha/ beta and their association with the expression of cyclin D1 and p53 in oral squamous cell carcinoma progression

Figure 3

The expression of GSK3α proteins at various stages of OSCC progression. (A) Representative immunostaining showing the differential expression of GSK3α and GSK3β from consecutive sections of lip SCC tissue progression, including (a, b) normal lip, (c, d) hyperplasia of the lip and (e, f) SCC of the lip. (B) Representative immunostaining showing the differential expression of GSK3α and GSK3β from consecutive sections of OTSCC tissue progression, including (a, b) normal tongue; (c, d) hyperplasia of the tongue and (e, f) SCC of the tongue. (C) Photomicrographs showing distant metastasis of SCC cells at the lymph nodes from various OSCC showing immunoreactivity to GSK3α and GSK3β antibodies to different extents in the consecutive sections (a to h). The metastatic OTSCC showed maximum expression of GSK3β (original magnification 100X).

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