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Table 2 Twenty-five differentially expressed miRNAs between triple-negative breast cancers and adjacent normal tissues a

From: Deregulated microRNAs in triple-negative breast cancer revealed by deep sequencing

miRNA

Raw p value

Adjusted p value

Triple-negative breast cancer

Adjacent normal tissue

   

Mean

Range

Mean

Range

   

Normalized

Min

Max

Normalized

Min

Max

hsa-miR-215

3.21E-08

4.66E-06

32

0

86

321

80

928

hsa-miR-497-5p

2.43E-06

3.49E-04

1980

354

6215

6520

2335

18692

hsa-miR-204-5p

4.69E-06

6.71E-04

98

0

569

2518

37

14352

hsa-miR-425-5p

5.98E-06

8.49E-04

23266

7198

57542

9180

4551

16066

hsa-miR-96-5p

1.34E-05

1.89E-03

4568

898

12421

1545

494

3892

hsa-miR-1301

1.72E-05

2.40E-03

592

0

4777

43

0

188

hsa-miR-335-3p

2.89E-05

4.02E-03

1173

118

4234

5591

440

11145

hsa-miR-183-5p

5.13E-05

7.08E-03

6223

1305

24697

1928

602

5753

hsa-miR-24-2-3p

6.04E-05

8.27E-03

6782

2062

17902

3254

1553

5731

hsa-miR-130b-5p

7.64E-05

1.04E-02

3729

1413

10634

1352

159

2856

hsa-miR-92a-3p

9.93E-05

1.34E-02

182

0

1151

0

0

0

hsa-miR-320a-3p

1.15E-04

1.54E-02

11490

0

29381

2273

0

26275

hsa-miR-130b-3p

1.23E-04

1.64E-02

550

204

1683

246

110

579

hsa-miR-145-5p

1.47E-04

1.94E-02

256

9

603

877

202

2457

hsa-miR-126-3p

1.55E-04

2.03E-02

44031

16691

108893

134103

29907

285350

hsa-miR-139-5p

1.57E-04

2.04E-02

693

181

2537

6623

307

23210

hsa-let-7a-3p

1.59E-04

2.05E-02

175

0

428

41

0

326

hsa-miR-489-5p

1.59E-04

2.05E-02

8

0

63

118

0

483

hsa-miR-362-5p

1.69E-04

2.15E-02

2216

1186

5092

1006

297

2303

hsa-miR-429-5p

1.91E-04

2.40E-02

6416

1486

23455

2082

406

8716

hsa-miR-19b-3p

2.43E-04

3.04E-02

569

0

3214

0

0

0

hsa-miR-362-3p

2.56E-04

3.17E-02

1043

565

2168

448

43

845

hsa-miR-320a-5p

2.72E-04

3.34E-02

1354

0

17859

4369

0

15247

hsa-miR-337-5p

3.44E-04

4.19E-02

386

9

961

1309

334

4086

hsa-miR-143-5p

3.91E-04

4.73E-02

43060

3104

99397

102717

29650

36464

  1. aNormalized miRNA reads from each sample were obtained after quantile-quantile scaling. The raw p-value of each miRNA was calculated using the log10-scaled miRNA expression data after quantile-quantile scaling and was adjusted using the Holm step down procedure. Relative expression levels are shown.