Figure 1From: MicroRNA modulators of epigenetic regulation, the tumor microenvironment and the immune system in lung cancer MicroRNA-mediated regulation of tumor microenvironment. The scheme demonstrates involvement of microRNAs in chemokine-mediated recruitment of regulatory T cells, monocytes, macrophages and MSCs and the role of microRNAs in tumor-related dysfunction of NK and cytotoxic T cells. All microRNAs are shown in red while gene targets and types of responses are shown in black. Arrows indicate directions of cause-and-effect relationships.Back to article page