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Figure 3 | Molecular Cancer

Figure 3

From: Male-specific hepatitis B virus large surface protein variant W4P potentiates tumorigenicity and induces gender disparity

Figure 3

Induction of IL-6 production by W4P LHB in a gender-dependent manner. (A and B) Serum levels of IL-6 (A) and TNF-α (B) measured from mice injected with NIH3T3, WT-LHB-NIH3T3 and W4P-LHB-NIH3T3 cells. **P < 0.01, ***P < 0.001. (C) Correlation between serum IL-6 levels and tumor volumes of W4P-LHB-NIH3T3-injected mice (10 male and 10 female mice) (r = 0.862, P < 0.001). (D and E) Serum IL-6 (D) and TNF-α (E) was measured in 11 HCC patients with WT and 11 with W4P variant sequences. **P < 0.01.

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Molecular Cancer

ISSN: 1476-4598