Figure 2

Effects of miR-93-5P transfection on ovarian carcinoma cell proliferation, cell cycle and cell apoptosis of ovarian carcinoma cell lines in vitro. Following miR-93-5P transfection, OVCAR3, HO8910-PM, SKOV3/DDP cell lines exhibited significantly slower growth and higher mature miR-93-5P mRNA expression (A), induced G₁ or S arrest (B), early apoptosis (C) and cleaved PARP expression (D) than the control and mock-transfected cells. Results are representative of three separate experiments; data are expressed as the mean ± standard deviation, *P < 0.05.