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Table 1 IRF5 interacting partners in MDA-MB-231 cells

From: A conserved region within interferon regulatory factor 5 controls breast cancer cell migration through a cytoplasmic and transcription-independent mechanism

Identified protein IRF5/EV ratio
Interferon Regulatory Factor 5 32.9
Tubulin alpha-1C chain 26.0
Mitochondrial heat shock 60kD 7.1
Similar to Homo sapien solute carrier family 25 5.5
Similar to transketolase 5.5
Similar to EF2 4.7
Filaggrin 4.7
Fructose-bisphosphate aldolase 3.1
Similar to protein disulfide-isomerase A6 2.7
Clathrin heavy chain 2 2.7
Flap endonuclease 1 2.7
Filamin-C 2.7
Triosephosphate isomerase 2.4
Myosin-9 2.4
Ribosomal protein L12 variant 2.4
Eukaryotic translation intiation factor 3 sub. D 2.4
Mannosyl-oligosaccharide glucosidase 2.4
U4/U6 snRNA Prp31 2.4
  1. Following immunoprecipitation of FLAG from FLAG-tagged EV- or IRF5-231 cells, IP lysate was analyzed by mass spectrometry. Binding of proteins identified was normalized to EV-231 FLAG levels. Proteins showing a greater than 2-fold increase in binding are shown.