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Table 1 Demographics and clinical characteristics of 56 newly diagnosed AML patients in this study

From: Sp1 and c-Myc modulate drug resistance of leukemia stem cells by regulating survivin expression through the ERK-MSK MAPK signaling pathway

Characteristics (n)

Survivin CD34+ expression, n (%)

CD34- expression, n (%)

Sex

  

Female (17)

8 (47%)

9 (53%)

Male (39)

23 (59%)

16 (41%)

P value

0.342

 

Age

  

≤40 years old (30)

19 (63%)

11 (37%)

>40 years old (24)

10 (42%)

14 (58%)

P value

0.226

 

FAB

  

M0 (5)

3 (60%)

2 (40%)

M1 (12)

10 (83%)

2 (17%)

M2 (8)

2 (25%)

6 (75%)

M5 (23)

17 (74%)

6 (26%)

M7 (8)

1 (13%)

7 (87%)

P value

0.148

 

Laboratory analysis (median)

  

WBC (109/L)

16.4

15.8

Platelet (109/L)

87

106

Hemoglobin (g/dL)

9.6

4.3

BM blast, %

36

21

PB blast, %

17

10

P value

0.174

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