Effect of paclitaxel and DCA alone and in combination on the growth of A549/Taxol xenografts in nude mice. (A-C)
In vivo growth of tumors in mice treated with DCA alone or in combination with paclitaxel was significantly inhibitedcompared with control mice, whereas treatment with paclitaxel alone had no effect. (D) Effect of vehicle, paclitaxel, DCA, or combined treatment on body weight. *P < 0.05. Data are mean ± SEM of three independent experiments.