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Figure 4 | Molecular Cancer

Figure 4

From: TP53 R72P polymorphism modulates DNA methylation in hepatocellular carcinoma

Figure 4

Impact of TP53 ARG72PRO on the expression of genes involved in DNA methylation metabolism. (A) Panel of liver cancer cell lines wild-type for TP53 used for in vitro experiments. (B) Western-blot analysis of p53 expression (baseline and doxorubicin-induced) in the panel of cell lines. +: indicates doxorubicin treatment, 0.2 μM/72 h. (C) qRT-PCR analysis of genes involved in DNA methylation metabolism. All cells were treated 48 h by 0.5 μM doxorubicin. P values are obtained by ANOVA analysis.

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