Skip to main content

Table 1 Characteristics of the 45 patients analyzed

From: TP53 R72P polymorphism modulates DNA methylation in hepatocellular carcinoma

ClinicoBiological features   n %
Gender Women 12 26.7
Men 33 73.3
Age mean ± SD 58.6 ± 11.6  
median 60  
range 28-79  
Risk factors anti-HCV 26 58
HBs Ag 10 22
anti-HBc 20 44
Cirrhotic liver   38 84
Tumor diameter mean ± SD 5.1 ± 3.6  
median 4  
range 1-13  
Point mutations TP53 9 20
β-catenin 4 9
AXIN1 0 0
Chromosome instability mean ± SD 29 ± 24  
median 20  
range 0-80  
  1. Chromosome instability is expressed as the fraction of chromosome arms lost in a given samples (chromosomes 1p, 4q, 6q, 8p, 9p, 17p were analyzed).
  2. HCV, hepatitis C virus; HBs Ag, surface antigen of hepatitis B virus; HBc, hepatitis B virus capsid/core.