Table 1 Characteristics of the 45 patients analyzed
From: TP53 R72P polymorphism modulates DNA methylation in hepatocellular carcinoma
ClinicoBiological features | Â | n | % |
|---|---|---|---|
Gender | Women | 12 | 26.7 |
Men | 33 | 73.3 | |
Age | mean ± SD | 58.6 ± 11.6 |  |
median | 60 | Â | |
range | 28-79 | Â | |
Risk factors | anti-HCV | 26 | 58 |
HBs Ag | 10 | 22 | |
anti-HBc | 20 | 44 | |
Cirrhotic liver | Â | 38 | 84 |
Tumor diameter | mean ± SD | 5.1 ± 3.6 |  |
median | 4 | Â | |
range | 1-13 | Â | |
Point mutations | TP53 | 9 | 20 |
β-catenin | 4 | 9 | |
AXIN1 | 0 | 0 | |
Chromosome instability | mean ± SD | 29 ± 24 |  |
median | 20 | Â | |
range | 0-80 | Â |