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Figure 1 | Molecular Cancer

Figure 1

From: Opposing roles for mammary epithelial-specific PPARγ signaling and activation during breast tumour progression

Figure 1

In vivo effects of MG-specific PPARγ loss on survival and total tumour outcomes. Overall survival outcomes for (A) PPARγ-WT and (B) PPARγ-MG KO mice are shown. Solid lines, DMBA Only treatment; broken lines, DMBA + ROSI treatment. Overall survival for (C) DMBA Only- and (D) DMBA + ROSI-treated mice are shown. Solid lines, PPARγ-WTs; broken lines, PPARγ-MG KOs. (E) Tumour incidences are shown for each strain across each treatment group for total, mammary, ovarian, liver, lung, skin and thymic tumours. *, p < 0.05; **, p < 0.01.

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Molecular Cancer

ISSN: 1476-4598