Skip to main content
Figure 2 | Molecular Cancer

Figure 2

From: Opposing roles for mammary epithelial-specific PPARγ signaling and activation during breast tumour progression

Figure 2

In vivo effects of MG-specific PPARγ deletion on mammary tumour incidence, tumour volume and latency. (A) Mammary tumour incidences, as well as incidences of benign and malignant mammary tumours, are shown for each strain across each treatment group. **, p < 0.01. (B) Mammary tumour volumes were calculated using the standard formula (L × W2/2) and are expressed as mm3 on a log scale. Solid lines, mean tumour volume for each strain; solid circles, PPARγ-WTs; open squares, PPARγ-MG KOs; *, p < 0.05. Mammary tumour latency is expressed as the percentage of palpable mammary tumours within (C) PPARγ-WT and (D) PPARγ-MG KO strains in a given week. Solid lines, DMBA Only treatment; broken lines, DMBA + ROSI treatment.

Back to article page