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Figure 4 | Molecular Cancer

Figure 4

From: Preclinical analysis of the anti-tumor and anti-metastatic effects of Raf265 on colon cancer cells and CD26+ cancer stem cells in colorectal carcinoma

Figure 4

The anti-tumor effect of Raf265 on HT29 and HCT116 cells. A. The average tumor weight of mice treated with Raf265 were shown. Data are presented as means ± SD from 6 nude mice and statistical analysis was performed by one-way ANOVA. *p < 0.05 versus the vehicle control group with the xenograft tumors from the corresponding cell lines. B. Representing diagrams of the IHC staining of CD31 (magnification: 400×) of the primary tumor from HT29 and HCT116 cells of the vehicle control group and treatment group were shown. At the lower panel, a bar chart presenting the scoring of IHC staining of CD31 based on the percentage and intensity of the positively stained cells under high power (400×) microscopy was shown. Data are presented as means ± SD from 6 mice in each group. *p < 0.05 vs saline group by one-way ANOVA.

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