Figure 1From: Long noncoding RNA PVT1 indicates a poor prognosis of gastric cancer and promotes cell proliferation through epigenetically regulating p15 and p16 PVT1 expression is increased in human gastric cancer tissues and correlates with poor prognosis. (A) Relative expression of PVT1 in GC tissues (N = 80) compared with corresponding non-tumor tissues (N = 80). PVT1 expression was detected by qPCR and normalized to GAPDH expression. (B) The PVT1 expression was significantly higher in patients with higher pathological stage (T3-4) than in those with lower pathological stage (T1-2). (C) The PVT1 expression was significantly higher in patients with deeper depth of invasion than in patients with shallower depth of invasion. Kaplan–Meier analysis of disease-free survival (D) or overall survival (E) was analyzed according to PVT1 expression levels. *, P < 0.05, **, P < 0.01.Back to article page