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Figure 1 | Molecular Cancer

Figure 1

From: Long noncoding RNA PVT1 indicates a poor prognosis of gastric cancer and promotes cell proliferation through epigenetically regulating p15 and p16

Figure 1

PVT1 expression is increased in human gastric cancer tissues and correlates with poor prognosis. (A) Relative expression of PVT1 in GC tissues (N = 80) compared with corresponding non-tumor tissues (N = 80). PVT1 expression was detected by qPCR and normalized to GAPDH expression. (B) The PVT1 expression was significantly higher in patients with higher pathological stage (T3-4) than in those with lower pathological stage (T1-2). (C) The PVT1 expression was significantly higher in patients with deeper depth of invasion than in patients with shallower depth of invasion. Kaplan–Meier analysis of disease-free survival (D) or overall survival (E) was analyzed according to PVT1 expression levels. *, P < 0.05, **, P < 0.01.

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