Figure 3From: Long noncoding RNA PVT1 indicates a poor prognosis of gastric cancer and promotes cell proliferation through epigenetically regulating p15 and p16The impact of PVT1 on tumorigenesis in vivo. (A) and (B) Scramble or shPVT1 was transfected into SGC-7901 cells, which were injected in the nude mice (n = 7), respectively. Tumor volumes were calculated every other day after 4 days of injection. Bars indicate SD. (C) Tumor weights are represented as means of tumor weights ± SD. qRT-PCR was performed to determine the average expression of PVT1. (D) Histopathology of xenograft tumors. The tumor sections were under H&E staining and IHC staining using antibodies against Ki-67. Error bars indicate means ± S.E.M. *, P < 0.05, **, P < 0.01.Back to article page