Table 2 Multivariate analysis for OS

Gender (Male vs Female)

0.56 (0.42-1.47)

0.264

Age (year, #0 vs >50)

0.58 (0.73-1.92)

0.227

Tumor location (colon vs rectum)

0.84 (0.86-1.46)

0.205

Lymph node metastasis (Yes vs No)

2.44 (1.69-5.42)

0.016*

Vascular invasion (Yes vs No)

2.27 (1.86-2.97)

0.035*

Distant metastasis (Yes vs No)

7.69 (3.27-16.38)

<0.001*

AJCC stage (I-II vs III-IV)

1.56 (1.21-4.85)

0.008*

PP4C expression (low vs high)

1.24 (1.02-3.59)

0.028*