Skip to main content
Figure 2 | Molecular Cancer

Figure 2

From: ZEB1 transcriptionally regulated carbonic anhydrase 9 mediates the chemoresistance of tongue cancer via maintaining intracellular pH

Figure 2

The ZEB1–CA9 axis regulates chemosensitivity in tongue cancer cells. (A and B) MTS cell proliferation assays showed that ZEB1 overexpression promoted resistance in Tca8113 and SSC-25 cells in response to PYM and cDDP, and that knockdown of CA9 abolished this effect. (C) Knockdown of ZEB1 enhanced the sensitivity of Tca8113/PYM cells to PYM and cDDP, while overexpression of CA9 attenuated this effect. * p < 0.01.

Back to article page