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Figure 3 | Molecular Cancer

Figure 3

From: ZEB1 transcriptionally regulated carbonic anhydrase 9 mediates the chemoresistance of tongue cancer via maintaining intracellular pH

Figure 3

The ZEB1–CA9 axis prevents pHi decrease induced by chemotherapy in tongue cancer cells. (A, C and E) The change in pHi found for each given cell line in response to PYM or cDDP treatment, as determined using the BCECF-AM pH fluorescence probe in conjunction with confocal microscopy. (B, D and F) Changes in apoptosis in response to PYM or cDDP treatment for each given cell line, as determined by Hoechst staining evaluated by fluorescence microscopy. * p < 0.01.

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Molecular Cancer

ISSN: 1476-4598