Next-generation sequencing reveals novel differentially regulated mRNAs, lncRNAs, miRNAs, sdRNAs and a piRNA in pancreatic cancer

Table 2 Expression of genes encoding pancreatic acinar cell secretory- and related proteins

	*PRSS1*	*CLPS*	*CTRB1*	*PNLIP*	*CPA1*	*CEL*	*CELA3A*	*PLA2G1B*	*CTRC*	*CELA2A*
N1	20.6	20.4	20.0	20.0	19.9	19.1	19.0	18.6	18.8	18.5
N2	20.8	20.3	20.3	20.2	19.9	19.2	19.2	18.8	18.3	18.5
N3	20.4	20.0	19.9	19.7	19.7	18.9	18.8	18.3	18.0	18.5
N4	20.1	19.5	19.8	19.3	19.7	18.6	18.3	18.0	18.3	17.3
N5	20.7	20.1	20.3	20.0	19.9	19.1	18.7	19.0	18.9	18.5
P1	13.4	12.8	12.8	12.4	12.0	11.2	11.2	10.4	10.3	10.3
P2	13.9	13.2	13.2	12.8	12.6	11.7	11.6	10.9	10.8	10.7
P3	14.4	13.3	14.1	13.5	13.4	12.4	12.1	11.6	11.8	10.9
P4	14.3	13.2	14.0	13.4	13.3	12.3	11.9	11.5	11.7	10.8
P5	13.8	13.2	13.2	12.8	12.5	11.6	11.6	10.8	10.7	10.7
P6	14.0	13.4	13.4	13.0	12.7	11.8	11.9	11.0	10.9	10.9
Mean N	20.6	20.1	20.1	19.9	19.8	19.0	18.8	18.6	18.5	18.3
Mean P	14.0	13.2	13.5	13.0	12.8	11.9	11.7	11.1	11.1	10.7
Log2 FC	6.4	6.9	6.6	6.8	7.0	7.1	7.1	7.5	7.3	7.6

The normalized logarithmic expression of the ten most highly expressed genes in normal pancreas tissues for all five control- (N) and six PDAC (P) sequencing libraries. All genes encode pancreas-specific proteins and are homogenously, highly expressed across all control libraries and more than ~100-fold decreased in all PDAC tissues.

ISSN: 1476-4598